A
Comprehensive Anti-Infection Approach
By: Stan Kurtz – Parent/Researcher
This is a DRAFT document – written 07/03/07
updated 10/03/07.
This document is
supported with medical literature, scientific data, clinical observations, and
parental reports. It also reflects
the observations, views and personal experience of the author who is a parent
(not a doctor). Mr. KurtzÕs perspective is driven from his personal experience
including his sonÕs recovery and from an evolving data pool in his online group
with 18,000+ posts from 1900+ families, many of which are sharing information
on what has worked and not worked for their child.
This document is
not intended in any way to be a substitute for professional medical advice.
This document is
an evolving work in progress. For
the latest version please visit www.recoveryvideos.com
Mr. KurtzÕs parental,
clinicianÕs, and researchers group can be found at: http://health.groups.yahoo.com/group/mb12valtrex/
Mr. KurtzÕs bio can be
viewed at:
The Early Origins of My
Antiviral Research
William Shaw Ph.D. was
the first person to suggest that I research antiviral therapies. My research
began by finding the works of Dr. Michael Goldberg, Dr. Jacquelyn McCandless and Dr. Sidney Baker. Through recovering my son, helping other families and observing a number of reports from families and physicians I quickly realized that a more comprehensive and individualized approach is what seems to work best for
the greatest number of children.
In less than a month after
starting an anti-infection strategy my son looked completely different. To me he looked recovered from his
major symptoms of autism. After my
sonÕs recovery I was quite surprised how very few doctors were treating autism
with an anti-infection strategy and how many of those who did not understand
the critical importance of a simultaneous
and comprehensive approach.
My current position is that
an antiviral (often a prescription but sometimes natural products) in
combination with an azole [24]
antifungal and some other prescription antifungals, as well as supplementation,
dietary intervention, and, at times, metals detoxification, given simultaneously
can successfully improve the health and symptoms of a child with autism and
related disorders.
What is Recovery From
Autism?
You cannot be cured of being
hit by a bus, but you can recover from it. You might even be able to recover enough that you do not
need to park in special parking spaces when you go shopping. If you are fortunate enough you might
recover well enough that you gain back so much of your functioning such that no
one would know you were ever in an accident.
This analogy mirrors my
belief about recovery from autism.
There are several degrees to this analogy. Some childrenÕs symptoms improve well enough that they start
functioning like neurotypical children.
They are still autistic but they are making great strides. To me, this means, Ògreatly
improved.Ó
Some childrenÕs symptoms
lessen to the degree that they lose their diagnosis. They are no longer considered autistic. This is one degree of recovery. Typically you might see children like
this having some residual symptoms of social, verbal, or learning nuances or
ADHD-type symptoms that might alert a specialist to suspect that the child once
had an autism diagnosis. For the
most part they are free of their symptoms and will likely lead what many would
consider a relatively normal life in society.
There is another form of
recovery where if you met the child in a room of his or her peers and did not
know the child had a diagnosis you would not be able to tell there ever was a
diagnosis. When I refer to recovery
I typically mean this level or maybe something arguably close. My son recovered from autism to this
degree.
When I say Ògreatly improved
or recoveredÓ that is a spectrum that means moderate improvement to significant
improvement from the childÕs symptoms all the way through to developmental
gains that make the child seem indistinguishable from his or her peers.
About MB12Valtrex - My
Family and Practitioners Group
In 2005, I founded of
MB12Valtrex, which is a unique group of families, practitioners, therapists,
and teachers (2000+ members and 18,000+ posts as of 8/07) who explore and help
develop these therapies and report clinical observations of children who are
using this comprehensive antiviral approach for individuals with autism
symptoms. This group is a great
way to execute these strategies and obtain direct feedback learn about how
parents and practitioners execute these therapies and what they observe through
the process. You can join this
group by going to the link below.
http://health.groups.yahoo.com/group/mb12valtrex/
About External Therapies
I continue to believe in
Speech, Occupational, Physical, Educational, Sensory Integration, and Behavior
Therapies as being an important part of recovery. I look at biomedical therapies, like this comprehensive
anti-infection therapy, as being similar to putting glasses on the brain and
free the body up to be able to utilize external therapies better.
About Autism
Some people talk about the
gifts of autism (or ADHD). If your
child had wonderful gifts but had a persistent pneumonia, recovering your child
from the pneumonia would not take away their gifts, and, in fact, it would
probably enhance them. I believe in the gifts that our children have, and I
also believe in giving them every possible chance to use them to their fullest
potential.
When I speak about autism I
usually mean autism as we understand the symptoms today, but I also believe
that many chronic illnesses often have a similar origin and modality as autism
symptoms. My school that includes
a combination of children with chronic illness, autism with ÒtypicalÓ children
we see many children and parents improve or recover from the symptoms of
illnesses and behaviors typically considered untreatable or incurable. This includes eczema, asthma, chronic
fatigue, fibromyalgia, irritable bowel, colitis, chronÕs disease,
diverticulitis, chronic viral infections, speech delay, sensory issues, food
allergies, aggression, sleep disturbance, drooling, chronic runny nose,
aggression, biting, anxiety, separation challenges, and more.
I have observed a surprising
number of parents and children with chronic illness recover from the same
therapies that help many children with autism. I believe that children with autism are some of the most
biologically involved cases of chronic illness. It has been my experience that when we find therapies that
work on children with autism, that the same therapies often improve and/or
preserve the health of many ÒneurotypicalÓ people and help recover some
ÒincurableÓ chronic illness conditions.
About Autism and
Comprehensive Antiviral Therapy
My current belief is that
autism is often a combination of pathogens and opportunistic infections often
combined with toxic body burden that reach a point of expression during
critical times of development in (commonly) a young, susceptible host.
Basically, I believe autism,
for many children, is an infection that interferes with the bodyÕs ability to
detoxify and causes a greater susceptibility to environmental toxins.
The goal of this
comprehensive approach is to disrupt the infectious cycle and allow the immune
system regain control over these intruders and then better detoxify from the
contributing toxins and inflammation that cause the autistic characteristics.
Viral and Other Infections in Autism
In my first search in PubMed,
the main database of peer reviewed medical literature, in 2004, I found 80
peer-reviewed viral/autism involved citations in the medical literature. To check peer-reviewed medical
literature, it is as simple as doing a Google search of ÒpubmedÓ going to that
site and doing a search for Òvirus autism.Ó Many of these papers included references to specific
viruses, inflammation, and autoimmunity.
Several of them specifically state the onset of the disorder surrounded
the onset of the infection. Three
case reports showed late onsets of 11 [1],
14 [2], and 31 [2] years old.
I think the average person
does not think of infections having a neurological effect, but if you just
think about how your brain feels when you have the flu or how a dog acts with
rabies we can begin to see quick examples.
In the case of Obsessive
Compulsive Disorder (OCD) or Tourettes Syndrome it was commonly believed to be
brought on by stress. Due to some
wonderful work by Sue Swedo, M.D., at the National Institute of Health many
cases were found to be the immune systems response to a Strep infection
(PANDAS) [29].
Other infections that are
linked to neurological issues include: Rabies, Lyme, HIV, Herpes, Polio,
Coxackie, Rubella, Borna, EpsteinÕs Barr (EPV), Eterovirus, Influenza, Measles,
Westnile - Borrelia, Shingles, Anthrax, Meningococcus, Mycobacterium, Syphilis,
Malaria, Chlamydia, Ricketts, and Candidiasis.
Infections that are in
implicated in the medical literature as causing or triggering cases of autism
include: Herpes, Rubella, Mycoplasma Pneumoniae, Shingella, Borna, Malaria,
Blastocystics, Varicella, Cytomegalo Virus (CMV), Syphilis, Toxplasmosis,
Neurocysticercosis, and Clostridium.
In reference to Clostridium, an interesting study was conducted by Dr. McFabe that showed injecting rats with propionic acid caused the onset of autism symptoms [32]. A main source of proprioic acid is Clostridia, a bacterial infection common in autism. My son had rasied levels of clostridia during his autism.
In my sonÕs case I believe he
was affected quite early on to some degree. He was born with eczema, had pale skin and his development
was at the late end of his milestones through his first 12 months. He then seemed to decline around the
time of his one-year vaccinations.
He had irregular hair growth, distended belly, dark puffy eyes, and was
hyptonic. In my experience and
opinion, eczema and related symptoms is a fungal infection of the inner layers
of the skin. Many people with eczema
appear to have gut issues that when properly taken care of seem to heal the
eczema almost immediately.
Some video examples include:
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Other evidence of how infectious activity can affect the brain includes three studies that show hypoprofusion (reduced blood flow to the brain) [33,34,35] and inflammation [36,37,38] in the presense of different types of herpes viral infections.
Secondary Symptoms and Observations of Bacteria and Fungus in the Autism Community
When I was younger and had bowel problems I now realize that I had lots of cavities, gum problems and bad breathe compared to other people. If my gums bled a lot in hindsight I wonder about my bowels. I also had adult acne and smelly feet. Additionally it only seemed like one deoderant worked for me, Secret. Hey, it really was strong enough for a man... with all that aluminum and all. Once I started working on my gut and adding MB12 that all went away.
I often hear reports of parents who had many cavities and fillings. Of course, many of us had dentists who used amalgams so not only did we have bacteria that eats away at the mouth but added to that was an almost endless amount of mercury for it to dig in to.
When I used a used an Arizona Instrument mercury vapor meter (Jerome 431-X) on the parents at my school I found that almost all of the parents were leaking toxic levels of mercury from their amalgams. Two of the three parents who did not leak mercury at all were chronic drinkers from my observation. I asked Boyd Haley Ph.D., about this and he suggested that maybe the alcohol broke down the mucosa from the mouth and the mercury was going straight in the skin. I was not getting any mercury excretion out of the hands of these people either, so this explanation did not make perfect sense to me.
My belief is that the alcohol kills off bacteria in the mouth (and possibly parts of the GI tract) and that is why the amalgams of these two moms weren't leaking.
I suspect the bacteria and fungal issue so common in parents of children with autism is doing harm in other ways as well. Since I started on working on my gut with an SCD-like diet (less IGG Food Allergies), antifungals, probiotics and Methyl-B12 Nasal Spray I stopped getting cavities, my gums stopped bleeding, and my incessant need to brush my teeth went away, my feet were much better, I could wear less deodorant and different brands, etc.
Smelly Breathe and Oily Skin Mixed With Dry Skin
There is this common smell on the breathe of many parents with autism. I also notice it at times with the kids as well. I also see a lot of oily foreheads, dry skin and thick rubbery palms. Certain fungus and bacteria make oily toxins and it seems they are often excreted from the forehead and the scalp. It seems the forehead and scalp specfically excrete these types of oily toxins. I suspect these toxic oils may also be blocking fatty acids from getting into the mitochondria. I visualize the cells blocking the fungal oils and at times secondarily causing fatty acid metabolism issues, dry skin, cholesterol and triglyceride challenges, fatty liver and myelination issues in the brain. Myelination happens in part through fatty acids and management of cholesterol. In my opinion, fungal and bacterial toxins could be a cause of some types of autisms.
I treated fungus and bacteria in my son and supplemented with essential fatty acids, l-carnitine, Co-Q10, and low dose niacin (higher doses can cause red ears and flushing).
About Thick Rubbery Palms
This seems to be common in folks with gut issues and/or mercury exposure (quite often amalgams). In a room full of people I can often tell who has amalgams just by feeling their palms.
I discovered this through my mercury vapor experiments. I found mercury is excreted moreso from the hands and feet than any other part of the skin. It seems that over time this exposure damages the palms of the hands and creates these rubbery feeling layers of toxic skin on the palms (and the bottoms of the feet).
There is a wonderful product to remove this type of damaged skin called 18MMM from GP Deva located on Rodeo Drive in Beverly Hills (310.858.6545). I have not found anything like it. In less than a minute you can have all that bad skin removed in a painless, effortless way. Just rub a little on and the bad skin falls right off. It unfortunately is $100 dollars a bottle but luckily a little goes a long way. If you find another product that works as well please let me know. I began using 18mmm on my entire family once I realized how important the hands and feet are at excreting toxins and heavy metals.
The Philosophy Behind The
Philosophy – Autism As An Environmentally Involved Infection
I do not personally
believe that vaccinations are the only cause of autism, but, as scary at it is
for some people to believe, in some children they seem to be a factor [15]. Many people talk about ÒtheÓ factor as being a genetic
predisposition, and for some that may be, but I believe that a transmittable
viral, fungal and/or bacterial infection at times combined with an exposure to
environmental toxins or vaccines may be a more frequent onset framework for
many children. If that is the case, then genetic patterns of children with autism is secondary to better understanding and treating the infections these children have.
There was a study in Kuwait
that showed that children with autism had much higher uranium levels than
controls, which were often their siblings. It is fair to say they had similar genes, and similar
exposure to toxins but ended up with dramatically different levels of uranium
in their hair [17]. This concept was very interesting to me
considering my son had uranium levels in his hair in excess of 14 times the
ÒsafeÓ levels of exposure. He also tested with high levels of candida (a
fungus) and clostridia (a ÒbadÓ bacteria) in his intestines. My belief is that my sonÕs raised
levels of fungus, bacteria, and possibly viral infection , which is quite common in children with autism,
made him more susceptible to environmental toxins.
In 1975, there was an interesting mouse study that showed if a mouse was exposed to coxsackie virus and cadnium that raised levels of metals could be found in the brain [31].
This is a common framework of
how the crossing of an infection and environmental toxins might lead to autism.
While trying to better understand how mercury is excreted by the body I did a mercury containing flu shot experiment. I injected myself with a flu shot and used an Arizona Instrument 431-X mercury vapor meter to track my mercury excretion. What I expected to see an immediate increate in mercury vapor, similar to what I had seen when I ate sushi which was an increase in minutes. With the mercury containing flu shot my levels dropped to practically zero. The levels went lower than just prior to the flu shot and they stayed near zero about the same amount of time I felt like I had flu symptoms which was about 7 hours. As soon as I felt better the mercury started pouring out of me.
It was a lesson learned by accident, but it seems to me that nature decides to worry more about infection than toxins.
My child may have had some
type of genetic predisposition, sure, but when I helped him take care of his
nutritional, fungal, viral, bacterial and toxic issues, he recovered. The Autism Research Institute has documented more than 1,000 cases of autism recovery through approaches that include infection and toxin management.
I believe if society weighs
genetics too heavily we may miss the opportunity to remove the
infectious and toxic issues commonly involved in many of our children with symptoms of autism.
A challenge for many parents
is to consider genetics as an element of the issue and not the cause,
especially when many pathogens, bacteria and fungus (some that we may understand
and some that we do not) can easily be passed down by sexual intercourse, birth and other transmissions.
I speak quite often to parents with chronic infections and toxins who blame the symptoms on their genetics because other family members are suffering from the same symptoms. "My whole family has allergies" or "We all have autoimmune issues," etc. Sadly, there are a lot of companies and organizations who benefit from other people not knowing they are chronically ill and that those ill people can recover.
I believe it is time for all of use to take responsibility for our own health and to not leave this critically important task in the hands of people who benefit from our illness.
In my experience, autism is
often a family illness with many family members having chronic energetic,
immunological, physiological, infectious and toxic issues. It should not take much effort to see
ADHD, OCD, autoimmunity, viral/bacterial/fungal infections, chronic anxiety,
depression and cancer within the immediate family of a child and/or the parents who are
affected by autism.
I often see families racing
to help their child only to lose sight that the child has the best chance of
recovery if the individuals in their family learn from and treat their own biological
issues.
Cases Of
Children Improving and Recovering
When I starting speaking to
the few doctors who treated their patients with autism I was quite surprised to
hear how many of their patients improved from antiviral therapy especially
considering how uncommon it was to hear of doctors treating children with
antivirals. I was also hearing
reports from doctors who said that many of their patients in the autism
community Òreact negativelyÓ to antivirals so they stopped using them.
The conflicting reports were initially
puzzling, but once my child began improving on this therapy I began to
understand the unique roller coaster process of improvement antiviral therapy
can provide for many children. I
focused on the nuances of this therapy in relationship to what works with
special consideration to some of the co-infections, toxins, and metabolic
challenges commonly found in children with autism.
I found that when addressed
comprehensively, antiviral therapy (really anti-infectious therapy) can often provide a child with symptoms of
autism the opportunity to experience a remarkable improvement and at times a seemingly complete recovery from their
symptoms.
Testing for Viral Therapy
You can ask your primary care
physician to order a viral titer analysis, which can be completed by any
regular laboratory and is often covered by insurance. Many people have run these tests and they can be helpful for
some children who do not respond to a trial of this therapy. However, many
children who respond well to antiviral therapy have had negative viral test
results, meaning they did not appear to have a testable virus. My son was one of them
Some people say these
children have difficulty creating antibodies to viruses. Some people say the therapy might be
affecting a virus that we are not yet aware of. Some people believe that this therapy is doing something
other than fighting viruses.
The bottom line is that there
is a real group of people who respond wonderfully to this therapy that never
test positive for a virus before, during, and after the therapy.
Who Should Try This
Therapy?
My conclusion, after
experiencing first hand and seeing many families report gains without positive
viral testing, is we do not yet know all the modalities that will benefit
children with autism and related conditions. The best way to see if your
child will respond, in my opinion, is a trial of the therapy.
How Long Is A Trial?
Based on reports from our parent and physician
group, it typically takes up to 50 days to see if a child will be a responder
to the therapy. Many times it is
much less and sometimes, although rarely, it can be longer.
The Healing-Regression
According to an ongoing
MB12Valtrex group poll, 38% of the families who try this therapy report what I
call a Òhealing-regression.Ó I use
the term healing-regression to best describe what sometimes happens when this therapy
is first put in place. Typically
the childÕs specific symptoms of autism will worsen for a period of 14 to 50
days and then is often immediately followed by developmental gains.
This response is different
than a herxhiemer response in that you typically see some small underlying
gains along with the regressive symptoms.
Since it seems
counter-intuitive that a short regression is a common part of this important
healing process, I spend a good deal of time observing and explaining the healing-regression.
Case Example
Here is a case example of a
4-year-old boy named Joseph who was doing biomedical interventions for 18
months with some mild gains but then tried the comprehensive antiviral approach.
Mom writes: ÒThe
regression began on day 4 with gains along with it. He became extremely
irritable, throwing things and tantruming and hitting people. While he
was hitting and tantruming we noticed he was actually looking us in the
eye. He rarely would look us in the eye without being prompted.
Since we began Valtrex [and the combination anti-infections along with it] in January 2006, his eye contact has been excellentÉ.
[Now two months later] he is about 80% recovered with expressive language
delay. Now he is basically
indistinguishable among the kids in the neighborhoodÉÓ
Not everyone who improves
does as well as Joseph, but a suprising number of children do.
Not everyone has the healing-regression either, some just improve.
Here is an open poll in our
group that asks about improvements and the healing-regression.
Healing-Regression Poll – 121 Responses
A Fungal-Eczema Rash
Compared to The Antiviral Rash
If there is not a proper
fungal strategy in place, the rash that may appear when you start your
antiviral therapy could be a fungal, eczema-like rash. This type of rash can interfere and
mask the underlying gains from the antiviral therapy.
Why do children with
autism have these fungal/bacterial flares so often?
It seems there is a
biological warfare going on within these children,
We received many reports of eczema-like fungal symptoms from our group when we first started tracking antiviral therapy. This was before families began combining antiviral therapy with antifungals, supplementation and dietary interventions. I have not found another community that reports a rash of this nature from viral therapy.
There is some evidence in the medical literature of a symbiotic relationship between viruses and bacteria, meaning that when you have a latent viral infection it seems to keep bacteria in check [30].
My belief is that within our
childÕs intestines a battle rages between high levels of pathogens, fungus, and
bacteria. If we disrupt one element we may allow another to propagate more
freely. This theory in combination
with the larger number of positive gains reported in our group is why I
advocate for a comprehensive approach to antiviral therapy that includes
antifungals, supplementation and dietary interventions at the same time.
A similar example of this
theory is demonstrated in a filmed interview I conducted of a man with chronic
fatigue and asthma that started dietary interventions and probiotics for his
symptoms. His symptoms quickly
improved and then the treatment appeared to mobilize what seemed to be a
smoldering underlying viral infection at the core of his symptoms. It seemed his fungal infection was
ÒholdingÓ his underlying virus at a low level. When he changed his diet it appeared that some of his fungus
and bad bacteria died off it then mobilized an underlying viral infection. He
then became quite ill with viral symptoms for about a week and then had a
wonderful recovery from his chronic fatigue and asthma.
Video Example: Mobilzing a Smoldering Virus With Diet and Probiotics
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For
more common throat infections, we often see reports of MB12 Nasal Spray being
immediately beneficial.
The
following link is a video example of a throat infection that was recovered in
minutes of MB12 Nasal Spray.
Video Example: Acute Viral Infection and MB12 Nasal Spray
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Assuming you have a
comprehensive viral, fungal and dietary approach in place and the rash is not
itchy and seems to be mobile and/or changes color during the day then you are
probably experiencing what I call an antiviral detox-rash.
The Antiviral Detox-Rash
and Possible Metals Dumping
My son developed a rash
during the therapy that did not itch and moved down his body from day 14 to day
21. It also seemed to change color
during the day. When the rash
moved down to his stomach he had several days of diarrhea and on day 21 he
looked better than ever.
I have polled the two largest
viral groups in Yahoo Groups, which consisted of more than 10,000 members, and
no one responded that they had rashes of this nature using antiviral
therapy. I interpreted that to
mean this rash and its underlying origin may be indigenous to our community,
and I often wonder if it is part of the core issue in some children with
autism.
Rash Poll – 77 Responses
In December of 2005, I
conducted a mercury-containing flu shot experiment on myself, and I had a rash
on my chest that was very similar to the one my son experienced. The rash on my chest tested positive
for high levels of mercury vapor.
This small experiment continues to be interesting to me as I
consistently see similar rash reports from parents during antiviral therapy.
The
Treatment Triangle Focused Metals Involvement
Antiviral Therapy and
Metals Detoxification
A growing number of families
are reporting that when they combine the comprehensive antiviral philosophy
with metals detoxification (for example chelation) they often see more heavy
metals excretion than with metals detoxification alone.
Metals Detox (DMSA) Example Without Antiviral
Therapy
What I find interesting about
these two test results is many of the toxic heavy metal excretion levels are
doubled from the initial test.
Symptomatically, this child was greatly improved to the point of being
unrecognizable among his peers within three months of starting the
comprehensive antiviral approach.
Metals Detox Example Combined With Antiviral
Therapy (2 months later)
Metals Detoxification and
Virus
Dr. Amy Yasko has postulated
that metal particles take up residence on the lining of a viral infected cell
and that treating with antivirals mobilizes that metal. This is one possible theory.
When I conducted a mercury
containing flu shot experiment on myself using a Jerome 431x mercury vapor
meter my mercury excretion levels dropped immediately after I received the flu
vaccine. This was a surprise to
me. The levels remained low for
about 7 hours and during that time I felt ill. When I began to feel better my mercury vapor excretion
levels went up dramatically. This
experiment led me to believe that the body is more concerned with a viral
infection than heavy metal excretion, and that a smoldering virus may
chronically interfere with the bodyÕs natural ability to protect against and
detoxify from heavy metals.
Summary Of Measurements – Mercury Containing Flu
Shot Experiment
In April 2006, a study was
published that demonstrated virally infected mice had higher levels of iron and
copper in their brains if there was also an exposure to cadmium [28].
We may not know the exact
modality why, but there is evidence that heavy metals may be more toxic to the
body in the presence of a viral infection.
The Methylation /
Adenosine Connection
Methylation, a key to health,
detoxification and neurotransmitter and DNA replication, is often impaired in
children with autism [4]. One of these impairments, found by Jill
James PhD. and observed by other researchers and physicians, is the abnormal
levels of adenosine. Adenosine has
the unique status of being a neurotransmitter and a metabolite involved in
methylation. Adenosine is also an
important anti-inflammatory.
This metabolic diagram,
provided by Jill James Ph.D., shows where abnormal levels of adenosine can
disrupt methylation, raise levels of SAH (a marker and cause of oxidative
stress) and lower levels of glutathione (the bodyÕs most important
antioxidant).
Dr. Sid Baker, in cooperation
with Jill James Ph.D., conducted a pilot study of 10 children with autism. Nine children were treated with
acyclovir and one child was not treated.
Note:
Valtex is quickly converted to acyclovir in the intestines and the liver5. From a viral treatment perspective many viruses that Valtrex
can affect can also take up residence in the liver. Valtrex is also more bioavailable than oral acyclovir6 (more similar to IV acyclovir) and
has what seems to be a safer side-effect profile.
In all the 9 children
adenosine levels were seemingly improved.
Some children had higher levels of adenosine and they were lowered. Some
children had lower levels and they were raised. The untreated childÕs level
remained unchanged. This striking
normalizing effect is not very common in medicine.
There are very few tools to
modulate adenosine and it appears that Valtrex is one of them. Mild Hyperbaric Oxygen Therapy (1.3
ATA) may be the only other therapy that I understand may affect adenosine. The only lab I am aware of that can
test for adenosine levels is Jill JamesÕ lab at University of Arkansas which is not publically available.
There is still much to learn
about why Valtrex and other antiviral therapies help so many children.
Additionally, there does not seem to be a way of measuring adenosine that is
easily available to the general population. This, combined with parent reports of children who improve
with negative viral testing continues to suggest that an antiviral trial may be
the best method to see if your child would be a responder.
Black Flecks
A subset of parents in our
group began reporting what they described as Òblack flecksÓ in their childÕs
stool (and about three reports of black flecks in the hair) during the early
stages of comprehensive antiviral therapy. Some people believe this to be part of metals
detoxification, others believe these are related to parasites, others believe,
in some children, these are related to scar tissue from an infection healing in
the intestines. I would like to
get them tested but I do not yet know of a lab that can help us. I am open to suggestions.
Either way this is an
interesting observation and we continue to see reports about these flecks.
Black Flecks Poll
What is Antiviral Therapy
Really Doing?
I am not sure we really
know. Some believe Valtrex (and
other antivirals) may be affecting viruses that we cannot test for (in addition
to the obvious ones that we can).
Some believe Valtrex is modulating adenosine in a way that improves
methylation. Some believe that in
some instances neither is right since we see some of the same symptom
resolution with Olive Leaf Extract, which works completely differently.
The bottom line is that we do
not really know all the answers yet, but many children improve when using this
therapy and when done properly the worst outcome is typically a temporary
healing regression with no gains.
The more common response is gains and, at times, recovery, which is what
happened in my sonÕs case.
My common sense tells me that
if a therapy has a low risk and many children have improved and some recovered
it makes sense to try.
The
Treatment Triangle Momentarily Focused On Fungus, Bacteria & Parasites
What Are We Really Dealing With?
There are hundreds of known bacteria and fungus in the gastrointestinal tracts of humans and I believe many we do not yet know. I believe there are bacteria strains in our kids that we do not have the knowledge to test for just yet. Yes, we often see high levels of candida, clostridia, e-coli, h.pylori and a lack of good bacteria in the gut. Some say it has to do with metals toxicity in the gut, but I believe that many of these kids are infected with strains of bacteria and/or fungus and/or viruses before these other downstream infections and toxicity occured. Could it be from the vaccines? Maybe in some, yes, but many children with autism have not been vaccinated. I believe there are a miriad of ways to get to the autism condition through infectious means. One way that has been interesting me is genetically modified organisms (GMOs). These are man altered bacterias used as pesticides. A recent California study showed that women who lived near farms had a far greater chance of having children with autism. What if the pesticide was in the form of a bacteria and that bacteria could cause not only a production of toxins but could kill off certain types of bacteria in the guts of our kids? Sounds like something out of a movie, but one such GMO that falls into the timeline of autism is Bacillus Thuringiensis.
This is only an early theroy, but I believe that in time we will find infections like the Bacillus Thuringiensis in these kids. Bacillus Thuringiensis can feed on lactobacillus and other good bacteria and create pesticides. It would be another explaination as to why so many of these kids have such disregulated digestive tracts and are so toxic.
Maybe it is Bacillus Thuringiensis or something like it causing the intestinal havoc in these kids or maybe not. Either way these kids quite often have a vicious bacterial and/or fungal and/or viral infections that seem to interact with each other and I believe we need to execute as much diligence as we can to go after this triangular infection comprehensively, simultaneously, and aggressively.
Natural Remedies
There are several natural
remedies that parents report benefits from. I will focus on a few that are supported by the medical
literature.
Antiviral, Antimicrobial
Alternatives
Olive
Leaf Extract (OLE)
Olive Leaf Extract is a
natural antiviral remedy that some parents have administered to their children
and reported gains in our group.
OLE can inhibit retroviruses like HIV-1 and prevent RNA to DNA reverse
transcription [7,8], inhibit cell-to-cell
membrane fusion [9], and may help
for colds and flu symptoms [10].
Some families have used OLE
as a primary antiviral therapy or as a secondary antiviral to Valtrex. Reports suggest considering OLE in your
trials to see if your child benefits from it. The typical dosage we see in our group is working up to 20
drops up to three times a day.
My child did not respond to
OLE but I have read reports of children who do.
Lauracidin/Monolaurin
Lauricidin are Monolaurin are
short chain fatty acids that I find very interesting because they not only seem
to help with some viruses like Cytomegalo Virus (CMV) [11], but can also act as an antibiotic
seemingly effective against Staphylococcus aureus, Mycobacterium terrae and
extremely effective against Helicobacter pylori [12].
Elderberry
(Sambucus)
Elderberry is a combination
of plants that seem to have natural antiviral properties. Elderberry has been shown to fight
HIV-1 [12], to shorten the symptoms
of influenza A and B [13], and said
to be very effective at treating symptoms of Avian Bird Flu H5N1 [14].
Oil
of Oregano (OoO)
Oil of Oregano has been
shown effective against Staphylococcus aureus, Escherichia coli, Klebsiella
pneumoniae, Helicobacter pylori, and Mycobacterium terrae [12].
Virastop
Virastop is a protease inhibitor that is said to break apart the wall of infected viral cells. There are no references in the medical literature to support its effectiveness and several people have challenged the science behind its claims but we do have some reports from parents that it has been helpful and since it is just an enzyme there seems to be no harm in trying it.
For more information about
enzymes you can visit: www.enzymestuff.com
Probiotics
There are many probiotics
acidophilus that seem to work well.
The probiotics below are additional suggestions that we commonly see
(either individually or combined with other probiotics) in positive parent
reports from our group.
Saccharomyces Boulardii (S. Boulardi)
Although the medical
literature is mixed regarding effectiveness of S. Boulardi, we see many reports
of it helping our kids particularly when bowel issues or clostridia is
suspected. If you focus on the
positive S. Boulardi medical literature, you will find may cases of positive
results.
Coconut
Kefir
Coconut Kefir is a fermented
probiotic used in the Body Ecology Diet [18]
and we have seen some really nice reports on its effectiveness. For more information on how to make it
visit:
http://bodyecology.com/coconutkefir.php
Fermented Foods
Fermented foods are a bit of
an effort but many families reports gains with fermented foods. Considering the impaired digestion and
disbiosis of our children, it may make sense to try fermented foods for their
easy digestion and probiotic properties
Antifungal Alternatives
Candex
Candex is an enzyme that
breaks down the cell wall of Candida.
I see reports of it working well on Candida and affecting intestinal
health. Candex often seems to cause
short-term diarrhea as the Candida dies off.
There are many non-medication
remedies said to help with fungus and products like Candex are worth trying but
when doing antiviral therapy we have not seen reports of non-medication
remedies working well by themselves.
It seems that azole antifungal medications (Nizoral, Diflucan, and
Sporanox) or Amphotericin B or Lamicil work best.
It is very possible for these
and other natural remedies to help our children in ways beyond what is listed
in the medical literature but you cannot tell until you do a trial.
Comprehensive Dosing Strategy (in my parent/moderator opinion)
Note: I am not a doctor and I do not give out medical advice. I am a parent who is just sharing information based on my own experience with my child and I am a moderator of MB12Valtrex where many families talk about their experiences. Every child is different and should be treated as an individual. Some doctors have expressed a concern about me stating specific dosages of medications, so I will refrain from doing so. What I do discuss openly is my philosophy about how a multidimensional and individualized approach seems to work best for many children. I believe that an indivualized diet in combination with an anti-infectious strategy for the specific child will often be beneficial. For specific dosing information, please speak to an enlightened, biomedically focused doctor. For a list of doctors please visit www.autism.com
1.
Keeping the dosing consistent across the day. According to parent reports it seem
that the sweet spot for antiviral dosing is three times a day.
2.
The Antiviral to Antifungal Ratio - Finding the
right ratio of antiviral administration to antifungal administration. This might be the most important
element of antiviral therapy.
Typically
a large percentage of children improve with just the common administration of
this therapy, but other times the therapy requires tweaking for a particular
child.
I
like to think about is as the right mix of air and gas for your car. Gas is important and without it the
process of ignition could not happen and if you donÕt have enough air the gas
will work against you.
I
think of Valtrex as kicking up and out the toxins and the antifungals as
cleaning up the fungal mess left over from the process.
When
you see a child starting this comprehensive approach and he or she starts to
become aggressive (and they may also have a whiter tongue or some topical skin
symptoms) most people think about lessening the antiviral. That may work as far lessening the
symptoms, but you may not have enough combined strength to shake this disorder
free.
As
they say, less is sometimes more, but sometimes more is more and this can be
one of those cases. To be on the
safe side (and typically more effective) I would make sure I was leaning more
towards having more antifungals onboard more often throughout the day and at
bedtime.
Getting
the dosing and the ratios of antivirals to antifungals can be part of the art
of this combination therapy for many kids. It is one of the reasons I created
the MB12Valtrex parent and practitioner group so feel free to join and share
your experiences and hear from others what they have done to help their kids.
3.
Choosing the right antifungal for your child
Typically
Nizoral and/or Diflucan, for example, are reported to work quite well for many children but not
always. Some children have
infections that are resistant to these medications. I believe that is why many of the families start the
antifungal before the antiviral.
This way they can start the antiviral and watch carefully for fungal
symptoms and better understand if the antifungal approach is effective for that
particular child.
Many
families who see a growing and consistent amount of aggression and
hyperactivity using this therapy change their antifungal medication to another
azole or use a combination of azoles and see their children greatly improve.
In summary, if you have the
right antifungal for your individual child and the right ratio of antiviral to
antifungal is on (meaning you have enough antifungal onboard compared to your
antiviral) your chances of success are much greater.
There are several variables
you need watch.
Is the diet and
supplementation right for your child?
The most common diet we see with comprehensive approach is The Specific
Carbohydrate Diet (SCD)19 less IGG Food
Allergies since it seems like the best way to control fungus. Some children might also require The
Low Oxalate Diet (LOD)20 if SCD less
IGG Food Allergies (alone) does not seem to work for them.
Is the antifungal right
for your child? Is this
antifungal helping your childÕs symptoms and does the antifungal hold up when
the antiviral is added in. Should
you add more antifungal throughout the day or do you need another
antifungal. Some parents consider
having two onboard at the same time.
It may be the most effective approach.
Is the antiviral right for your child? What we see most effective in order of reports is: Valtrex, Olive Leaf Extract, and Lauracidin/Monolaurin. Some people start with Valtrex and add or pulse the other two in to see if they are effective (see pulsing below).
Nystatin Vs. Azole Antifungals
(Diflucan, Nizoral, Sporonox) and
Lamisil and Amphotericin B.
One of the most common mistakes I have seen is an administration of Nystatin during the antiviral therapy. In traditional medicine, I am told that Nystatin is preferred with pediatricians because it is designed to stay in the intestines and is easier on the liver. We have seen consistent reports of significant and persistent fungal flare symptoms with this method. It seems that in hundreds of reported cases that Azole antifungals (or Lamisil or Amphotericin B) are the best strategy. This may have to do with the entire body being involved in this infection or some other property of these antifungals.
After seeing this mistake
made time and again with a success rate of less than 5% per parental reports,
to me it seems to be a waste of time to engage in antiviral therapy with
Nystatin as your fungal strategy.
Summary of Tools For Anti-Infection Treatment
Here is a draft summary of different tools to consider in the Anti-Infection Strategy. I believe this is a good way to view your approach by considering all the sides of the treatment triangle at the same time. You might want to use this as an outline to talk to your DAN! doctor about and to have handy as you discuss your strategy in our family and practitioner group. Join here.
The Antifungal, Probiotic, and Dietary Elements Are
Critical
Parent reports have
consistently indicated that the antifungal strategy is one of the most important
elements of the comprehensive approach.
We have seen most cases of success (possibly all) have a solid azole
antifungal (or Limisil or Amphotericin B) onboard for the entire therapy. Here is a recent report from a family
whose doctor made the mistake of not keeping the antifungal onboard during the
entire therapy.
ÒWhen my
son went on Valtrex, his DAN doc put him on Diflucan for 2 weeks prior, then
removed it, then started him on Valtrex. She told us that doing the
Diflucan before would take care of his gut and that he would not need it
during. For us, this was a HUGE mistake. After three weeks on
Valtrex, the 1st at 1/2 dose then increasing to full dose, my son went from a
happy little boy who slept through the night to a child who could not hold
himself together for more than 10 mins at a time, having complete emotional
breakdowns crying, screaming fits and kicking 24 hours a day and all
through the night. Large doses of Goldenseal 2x/day worked wonders but I
at the time I was so scared, I took him off Valtrex. If I ever were to
try it again, I would never do it without a [antifungal] script on board the
entire time. He did experience benefits from the Valtrex even at half
dose but in no way did the negatives outweigh the positives.Ó
Just my 2
cents....
Elen
This was followed
by another report,
ÒIf I may add....we
experienced the same our 1st go round w/out a rx on board. 2nd attempt went
much better with Diflucan and Nizoral being rotated. We are on month 4 with
some great results!!Ó
Angie
Comprehensive Antiviral Therapy – A Typical Administration Used In Our Group
In my sonÕs case, he was
28-32 lbs during the 9 months we kept him on this therapy. Much of this therapy is based on his
particular body weight since that is what I have first hand experience
with.
Parents typically work
closely with their doctors to find the right dosages for their specific
child.
Step 1: Diet
Since antiviral therapy seems
to uniquely kick up yeast and fungus in our children, it seems important to
make sure you avoid feeding your child foods that may cause an opioid response,
can disrupt the immune system, or can feed fungus and/or bacteria.
á
Consider eliminating
Gluten and Casein (all milk and wheat products) and any IGG Food Allergies (in
reality it is IGG sensitivities)
á
Reduce or eliminate
complex carbohydrates and starches
á
Purchase Organic Foods
á
Juice organic vegetable
and fruit for children who have difficulty with vegetables. See my juicing video for more
information.
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This step can cause a
temporary regression from the reduction in levels of opioids caused by the
foods and/or through fungal die off.
Diets for our children are an
art and discipline in itself. Some
families report gains regardless of the diet, but more families report an
easier and more effective journey when the proper diet for the particular child
is in place. I do not want to
discourage a parent fearful of dietary interventions from trying this therapy,
but at the same time if you want to increase your chances of success having
the right diet in place seems to play an elementary role.
Step 2: Supplementation
I suggest getting an Organic
Acid Test or a Metabolic Assay Profile to see what supplements your child may
need. Also consider going on an
MB12 Nasal Spray or Sub-Q injection trial.
My son was typically on the
following:
Epsom Salt Baths (very
important for this therapy), Vitamin C, Vitamin B5, B2, L-Carnitine, Cod Liver
Oil, Calcium, Niacinamide (B3), Zinc, Calcium and Super Nuthera.
Many families are careful to
add one supplement at a time to better understand if the child has a specific
challenge with a particular supplement.
Probiotics often cause a
temporary die off that takes several days and is often followed by gains.
Step 4: Probiotics
My son was taking probiotics at night on an empty stomach. There are many types of beneficial probiotics. Typically if you find one that works for your child you may see an initial die off often followed by some type of beneficial gain. Acidopholus, S. Boulardi, Cocunut Kefir, and fermented foods are a few common examples of probiotic strategies.
Step 5: Antifungals
We have an overwhelming
number of reports from parents about yeast-like flare-ups when this therapy is
initiated without antifungal medications.
Typical natural antifungals are not typically effective for our
community.
We have seen families
successfully use 50 to 200mg of azole antifungals like Nizoral (which is what
we used), Diflucan, Sporonox.
Additionally some families successfully use Lamicil and/or Amphotericin
B. Our child was on 50mg of Nizoral two times per day (generally in the morning
and at bed time). Some children
have been reported to require more.
We also used activated charcoal (put in organic apple sauce) for the
first week of die off symptoms.
It is important to work
closely with your doctor to find the antifungal that best suits your childÕs
specific condition.
Step 6: Antivirals
Once your child has adapted
well to steps 1-3, you may want to start your antiviral therapy with your
choice of antiviral. We have had
reports of gains with Olive Leaf Extract, Lauricidin, Monolaurin, Virastop and
some other non-drug antiviral therapies, with some of them leading to very
significant gains in certain children.
That said, Valtrex is by far the method of choice for the largest number
of children. Some try the naturals
first. More people seem to try
Valtrex first and then add in the naturals if they do not get the results they
want.
In our case, we only used
Valtrex as the antiviral.
We started with a 1/4 dose
for a few days and then worked our way up. We ended up giving 250mg of Valtrex three times a day
(remember that our child was 28-32lbs).
The blue coating of the tablet has an aluminum product in it that some
children react to. I suggest
washing off the blue coating first, then crush the pill with a pill crusher,
shake vigorously in juice, then let it dilute for 15 minutes and shake again.
We have seen reports of gains
as low as 1/8 the typical dosage.
Some people feel lower doses work best for their child, some feel the
best gains came from higher doses and their child needed to go through a
healing-regression to get there.
These are typically parental or physician guided choices and are often
part of the art of customizing the approach to fit the specific child.
People also often ask
questions about dosing for older and larger children. Sometimes Òless is moreÓ when it comes to this therapy so
there is nothing wrong with starting or staying at lower doses if you feel that
is what works best for your child.
That said, on page 13 of the
Valtrex Prescribing Information document it suggests 1000mg three times a day
for adults with herpes zoster5,
so it might make sense for some larger children or adults with autism try
higher dosages if smaller dosing does not seem to be working. This is, of course, between you and
your physician to decide.
Why Three Times A Day?
We often see reports that
demonstrate better results when families are dosing three times a day. We havenÕt conducted any polls, but the
half-life of Valtrex is 2.5 hours so when considering the possible affects on
methylation it may make sense to keep a stable amount of the medication in the
child. We dosed three times a day.
Step 7: (Optional)
Inflammatory Relief
Part of the
healing-regression may be inflammation related to processes like kicking up the
underlying infection or the release of toxins. We have seen some beneficial reports of parents doing
Cranial Sacral therapy during this period.
We also have some positive
reports of families doing low doses of steroids (like 5mg of prednisone) for
the short term of the healing-regression (typically 14 to 50 days).
I also wonder if
Spironolactone might be helpful based on the recent publication by Bradstreet
et at. 26 discussing its
anti-inflammatory properties.
Step 7: Try To Wait
Patiently
During the first 50 days you
might see fevers, pox, a non-itchy, mobile rash, stool changes and other
healing-regression symptoms. It is
not always easy to watch your child go through this, but try to put it in
perspective. This therapy does not
typically cause any negative looking affects to the typical community. What we see is typically part of the
healing or clearing out of this terrible disorder. It is not typically caused by the therapy; it is typically
caused by the die-off, detoxification, and healing.
Why is there a
healing-regression?
There is no other community
that I have found that responds to antiviral therapy like ours. I have
personally tried ultra-high doses of Valtrex on myself without an antifungal
and I cannot replicate a healing-regression. I also have not seen a report in any other population that
is similar to reports that we see when our children are healing. Based on my sonÕs experience and seeing
so many children improve after a healing-regression I believe it is a critical
part of the healing process for some children. I also believe that leaving whatever we are kicking up
inside our child, meaning not addressing this issue head on, may likely more
long-term damage and lessens our chances of getting our kids back.
To me, the healing-regression
may be, for some, possibly many, at the core of the condition itself. Some parents are even disappointed that
their child didnÕt go through this healing-regression because they know their
child may not be a responder to the therapy.
Here is my sonÕs recovery
video for a little encouragement if you need it.
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What is a
healing-regression and what is a negative reaction?
This can be a challenging
question. Typically the
healing-regression looks like your child is more autistic but also has some new
subtle developmental gain(s) possibly in eye contact, speech, balance, or
socialization.
A negative reaction might
look like a full-on fungal flare in which case many people consider changing or
increasing their antifungal strategy.
Another type of negative
reaction might be a healing-regression or regression that lasts for 50 days
with no gains in sight. If you
decide to stop the antiviral therapy the child should look like they did prior
to therapy in just a couple of days.
Many people who do not see
gains with Valtrex try switching to Acyclovir, Famvir, or Olive Leaf Extract
and find gains with those therapies.
While a majority of families report gains through this therapy, some do
not see improvement on any of these therapies.
Just like any therapy, if you
have tried all the variations that you feel comfortable with and you do not see
progress, I would move on to other therapies continue doing trials until you
find a therapy that works for your child.
Step 8: Pulsing
Some people mix the natural
antivirals into the therapy during a 5-day (Valtrex) and 2-day (natural, like
OLE or Lauricidin/Monolauren) or 3-day (Valtrex) 1-day (natural
If the therapy does not seem
to be creating improvements during the trial period (up to 50 days), then some
families have tried pulsing the therapy.
We did not have to pulse the
therapy for my son but the concept of pulsing makes more and more sense to me
especially if you want to mix in trials of natural treatments.
Pulsing came about when
parents thought the therapy was not working and stopped administration only to
find their child have a rash, a pox, or a cold sore breakout immediately after
discontinuing the therapy. We are
not sure why, but it seems in these cases there is a two stage process going
on. It seems that the therapy
itself does one-half of the cycle of work and stopping does the other. In these cases some parents have moved
to a five day ÒonÓ and two day ÒoffÓ or three day ÒonÓ and one day ÒoffÓ
schedule.
I would not stop the
antifungal strategy on the ÒoffÓ days.
On the off days you may want
to consider mixing in natural remedies, mentioned earlier, and if you see
consistent gains from those remedies you might want to consider keeping them on
throughout the week.
The key to this therapy is
learning what works best for your specific child.
My child was on Valtrex and
Nizoral for 9 months straight with consistent gains until about 9 months. If I had a diagnosed child today I
would probably be mixing in natural remedies and consider a pulsing trial to
see if the therapy was working optimally.
When to Stop
In my sonÕs case I didnÕt
want to stop as long as I was seeing gains. I have seen case reports of parents stopping after two
months (sometimes because their child looks recovered) and then the child
regresses. We kept going until my
son seemed to plateau at 9 months.
At that point, I took him off of all his biomedical therapies except the
diet. He immediately began
progressing again. I waited two
weeks and ran an Organic Acid Test from Great Plains and found it markedly
improved. The only thing that was
indicated was L-Carnitine. I kept
him on L-Carnitine, Vitamin C, Fatty Acids and the diet and he has been on that
regiment for almost three years now and is doing wonderfully.
In short, I would look for
your child to ÒtellÓ you when they no longer need the therapy.
Summary
Like many therapies,
antiviral therapy does not work for all children with autism. For some children this will be an
important part of the journey. For other children it will be a tool for
recovery. Diet and supplementation
were important for my son, but once that was in place I believe antiviral
therapy is what took him the rest of the way. Since it seems to work for many children and it seems
relatively safe, I believe in doing a trial and using this type of
comprehensive approach and seeing for yourself.
With hundreds of families in
our online group, you do not need to do this therapy alone. Feel free to join MB12Valtrex in Yahoo!
Groups and read and share stories of trials with other parents and some
practitioners.
I wish you and your family
all the best in your recovery journey.
Stan Kurtz
Citations:
1 - Ghaziuddin M et al., Eur Child Adolesc Psychiatry. 2002
Jun;11(3):142-6. Autistic symptoms following herpes encephalitis.
(PMID: 12369775)
2 - Gillberg C, J Autism Dev Disord. 1986 Sep;16(3):369-75. Onset
at age 14 of a typical autistic syndrome. A case report of a girl with herpes
simplex encephalitis. (PMID: 3558293)
3 - Gillberg IC, Dev Med Child Neurol. 1991 Oct;33(10):920-4. Autistic
syndrome with onset at age 31 years: herpes encephalitis as a possible model
for childhood autism (PMID: 1743418)
4 - James SJ et al., Am J Clin Nutr. 2004 Dec;80(6):1611-7. Metabolic
biomarkers of increased oxidative stress and impaired methylation capacity in
children with autism. (PMID:
15585776)
5 – GlaxoSmithKline,
Valtrex Prescribing Information, downloaded 7/5/07, http://us.gsk.com/products/assets/us_valtrex.pdf
6 - GlaxoSmithKline, Valtrex
Prescribing Information, downloaded 7/5/07, p3. http://us.gsk.com/products/assets/us_valtrex.pdf
7 - Bao J
et al., FEBS Lett. 2007 Jun 12;581(14):2737-42.
Computational study of
bindings of olive leaf extract (OLE) to HIV-1 fusion protein gp41. (Pubmed 17537437)
8 - Biochem Biophys Res Commun. 2003 Aug
8;307(4):1029-37.
Anti-HIV activity of
olive leaf extract (OLE) and modulation of host cell gene expression by HIV-1
infection and OLE treatment. (PMID:
12878215)
9 - Micol V
et al., Antiviral Res. 2005 Jun;66(2-3):129-36. The
olive leaf extract exhibits antiviral activity against viral haemorrhagic
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15869811)
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Jurenka J,
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May JT
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of antimicrobial factors in human milk on rhinoviruses and milk-borne
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A new triple combination
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study of the efficacy and safety of oral elderberry extract in the treatment of
influenza A and B virus infections.
(PMID: 15080016)
14 - Pressbox.co.UK, 2006, Laboratory
tests show Sambucol¨ neutralises Common and Avian Flu Virus H5N1, downloaded from the Internet 7/5/07 http://www.pressbox.co.uk/detailed/Science/Laboratory_tests_show_Sambucol_neutralises_Common_and_Avian_Flu_Virus_H5N1_52108.html
15 – Rimland, Bernard
Ph.D., 2005, Video: ÒHow many people believe and have evidence that their
child became autistic after vaccinations?Ó, DAN! Conference question to an audience of 900+ families., http://www.childrenscornerschool.com/video/mercuryhandraise.wmv
16 - Rowland
IR., et al., Experientia. 1975 Sep 15;31(9):1064-5. The
methylation of mercuric chloride by human intestinal bacteria. (PMID: 1100426)
17 - Fido A,
Al-Saad S.,
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elements in the hair of children with autism, (PMID: 15937043)
19 – Gottschall,
Elaine, Breaking The Vicious Cycle - Homepage, http://www.breakingtheviciouscycle.info/
20 – Susan, The
Low Oxalate Diet (LOD) Yahoo! Group, http://health.groups.yahoo.com/group/Trying_Low_Oxalates/
21 – Kurtz, Stan,
2005, Video: Elaine Gottschall Tribute – The SCD Diet, http://www.childrenscornerschool.com/video/elaineweb.wmv
22 – Kurtz, Stan,
2005, Video: William Shaw PhD, - Food, Immune Reaction, http://www.childrenscornerschool.com/video/Drshaw.wmv
23 – Pecan Bread, The Specific Carbohydrate Yahoo! Group http://health.groups.yahoo.com/group/pecanbread/
24 – ÒAzole
AntifungalsÓ, Nizoral, Diflucan,
Sporanox, http://www.drugs.com/cons/antifungals-azole.html
25 – The Body
Ecology Diet Homepage: http://bodyecology.com/
26 - Bradstreet JJ, Smith S,
Granpeesheh D,
El-Dahr JM,
Rossignol D
Med Hypotheses. 2007;68(5):979-87. Epub 2006
Dec 5. Spironolactone might be a desirable immunologic and hormonal
intervention in autism spectrum disorders. (PMID: 17150311)
27 - Heintze U, et al. Scand J Dent Res. 1983 Apr;91(2):150-2.
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